PhD Students

I am a chemist with ample experience in NMR spectroscopy-based structure elucidation.  My PhD project entails exploring the use of NMR as an analytical tool for the delineation of complex mixtures of organic compounds of biological origin. The aim is to assess and monitor metabolomic response profiles to external stimuli or genetic modifications with a focus on understanding any systematic changes using statistical means. The project involves establishing appropriate and systematic sample development procedures and NMR experiment parameter sets for metabolomics as well as introducing 13C and 15N isotopes to study biosynthesis and potentially track biotransformation of secondary metabolites. The findings of the project will be corroborated with orthogonal omics data obtained within CeMiSt.

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I am a natural product chemist, with a focus on analytical chemistry and metabolomics. My PhD project is centered around in situ detection of secondary metabolites via high resolution LCMS/MS, GC-MS, and MALDI-MS imaging. Typically, microbes are studied in laboratory contexts in conditions that differ greatly from their true natural environments. To better understand how and why bacteria produce metabolites, my project is developing and refining various analytical techniques for observation of secondary metabolites in situ, directly from the environment, including both terrestrial and marine soil, as well as fully aquatic systems and biofilm-organic matter interface systems.

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I am a biotechnologist with a background in whole genome sequencing of soil bacteria, particularly actinobacteria. As a PhD student at CEMIST, I will study the biosynthetic potential of soil bacterial communities and the expression of biosynthetic gene clusters found in these communities.

This will primarily be done by hybrid sequencing, using a combination of Oxford Nanopore and Illumina sequencing, to create metagenomic and metatranscriptomic data from soil samples and model communities.

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My project utilizes long-read metagenomics and metatranscriptomics to explore the biosynthetic potential of marine sediment microbiomes found across Denmark. By analyzing complete genomes, actively expressed genes, and the metabolome, we aim to understand the ecological role of specialized metabolites within the marine sediment microbiome.

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My project focuses on marine bacterial interactions and the role and function of associated secondary metabolites. My work includes establishing co-cultivation of marine bacteria, and the use of classical microbiological techniques and omics approaches to study these systems.

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I am a pharmacist specializing in analytical chemistry. My expertise lies in the development of analytical methods that utilize liquid chromatography coupled with mass spectrometry, sample preparation techniques, and their applications for targeted and non-targeted analyses. Currently, I am engaged in a doctoral research project whose main aim is to enhance our understanding of natural product biotransformations, particularly concerning the chemical interactions among secondary metabolite-producing microorganisms within two specific ecological niches: marine biofilms and soil from Dyrehaven National Reserve Park. This project primarily encompasses analytical natural products chemistry, emphasizing microbial extractions, isotopic labeling of key metabolites to investigate biotransformations, and various mass spectrometry techniques including LC-MS/MS and MALDI-ToF MS. Additionally, I will employ MALDI Imaging to spatially map biotransformations within the microbiome and its associated metabolome

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