Postdoctoral Researchers


I am a Postdoc at the Center for Microbial Secondary Metabolites at DTU Bioengineering. I have a background within bacteriology and microbial ecology. My PhD project focused on the impact of secondary metabolites on the ecology and evolution of Bacillus subtilis in soil derived communities. My work include secondary metabolite profiling on soil, genetic modification, and transposons insertion sequencing analysis to understand the function of secondary metabolite on bacterial physiology and development in the soil





My research background is in natural products chemistry with an interest to identify bioactive compounds from natural sources that can benefits pharmaceutical and agricultural research. My current project is focused on chemical profiling of bioactive secondary metabolites from soil Actinobacteria using LCMS-based metabolomics and NMR spectroscopy. The aims are to identify compounds that play roles in plant-microbe interactions and to investigate those beneficial molecules for their applications in agricultural perspective.





I am a postdoctoral researcher specializing in natural products chemistry and the chemical analysis of complex microbial systems. My background is quite multidisciplinary, with expertise in microbial interactions involving fungi and/or bacteria, natural products isolation and characterization (NMR, LCMS), and the subsequent interactions of such natural products in biological systems. My work here at CeMiSt aims to understand the ecological role of natural products in environmental microbial systems through the use of LCMS-based metabolomics and the development of novel co-culture and chemical analysis tools.


I am a molecular microbiologist with background in soil microbiology and a focus on microbial community response to changes in the soil environment using transcriptomics and metatranscriptomic analyses .I have joined CeMiSt April 2021 to understandi the role of secondary metabolites in a microbial community thorough transcriptomics and metatranscriptomics analyses. My work is also focusing on investigating and developing extraction protocols for RNA from environmental samples, such as Bryozoa and soil, and co-culture of microalgae with secondary metabolite producing bacteria.




My current research is centered around utilizing synthetic biology to improve our understanding of specialized metabolites and their potential role(s) in natural environments. In my research, I build genetic circuits that respond to the presence of specialized metabolites with an output measured as genetic memory. The tunable sensitivity of these circuits will potentially allow for greatly improved in situ detection of microbially produced specialized metabolites. I aim to develop a number of circuits responding to diverse metabolites and use them to record the presence of specialized metabolites in natural environments, such as soil and to investigate chemical metabolite signaling in microbiomes.


I am Postdoc at the Center for Microbial Secondary Metabolites at DTU Bioengineering. I have a background within microbial evolution and marine microbiology. My PhD project focused on the effects on microbial diversity and functionality of marine microbial communities as a function of key secondary metabolites. My work includes the development and use of marine model systems, that allow studies of the evolutionary effects of secondary metabolites on microbial communities.








 
My research is focused on (1) understanding the ecological role of ribosomally synthesized and post-translationally modified peptides (RiPPs) in natural and engineered systems, and (2) implementing new LCMS-based metabolomics tools like GNPS molecular networking to help answer the biological questions explored in the center. RiPPs are found in all kingdoms of life and their broader ecological roles are not well understood. Using multi-omics, I aim to investigate the ecological impact of RiPPs through known and new chemistry via the CeMiSt systems. LCMS-based metabolomics provides an unparalleled service for the analysis of complex organic extracts. I am involved in implementing and developing tools on the GNPS platform, providing innovative metabolomics tools that aid in everything from drug discovery to chemical ecology.


I have a background within bioactive natural product discovery from plants and marine Streptomyces, and extensive experiences in investigating microecological factors in the rhizosphere. My research within CeMiSt focuses on unravelling the interactions among soil microorganisms, natural products and plants. Combining advanced techniques in natural product chemistry, metabolomics, transcriptomics analysis and plant assays in different environment, I am investigating the natural plant-growth promoters from soil Streptomyces and understanding their mechanisms of action. Beneficial Streptomyces and metabolites can be further developed as environmentally friendly biological solutions to benefit modern agriculture.