Postdoctoral Researchers

I am a Postdoc at the Center for Microbial Secondary Metabolites at DTU Bioengineering. I have a background within bacteriology and microbial ecology. My PhD project focused on the impact of secondary metabolites on the ecology and evolution of Bacillus subtilis in soil derived communities. My work include secondary metabolite profiling on soil, genetic modification, and transposons insertion sequencing analysis to understand the function of secondary metabolite on bacterial physiology and development in the soil

I am a molecular microbiologist with background in soil microbiology and a focus on microbial community response to changes in the soil environment using transcriptomics and metatranscriptomic analyses .I have joined CeMiSt April 2021 to understandi the role of secondary metabolites in a microbial community thorough transcriptomics and metatranscriptomics analyses. My work is also focusing on investigating and developing extraction protocols for RNA from environmental samples, such as Bryozoa and soil, and co-culture of microalgae with secondary metabolite producing bacteria.

My current research is centered around utilizing synthetic biology to improve our understanding of specialized metabolites and their potential role(s) in natural environments. In my research, I build genetic circuits that respond to the presence of specialized metabolites with an output measured as genetic memory. The tunable sensitivity of these circuits will potentially allow for greatly improved in situ detection of microbially produced specialized metabolites. I aim to develop a number of circuits responding to diverse metabolites and use them to record the presence of specialized metabolites in natural environments, such as soil and to investigate chemical metabolite signaling in microbiomes.

I am Postdoc at the Center for Microbial Secondary Metabolites at DTU Bioengineering. I have a background within microbial evolution and marine microbiology. My PhD project focused on the effects on microbial diversity and functionality of marine microbial communities as a function of key secondary metabolites. My work includes the development and use of marine model systems, that allow studies of the evolutionary effects of secondary metabolites on microbial communities.

My research is focused on (1) understanding the ecological role of ribosomally synthesized and post-translationally modified peptides (RiPPs) in natural and engineered systems, and (2) implementing new LCMS-based metabolomics tools like GNPS molecular networking to help answer the biological questions explored in the center. RiPPs are found in all kingdoms of life and their broader ecological roles are not well understood. Using multi-omics, I aim to investigate the ecological impact of RiPPs through known and new chemistry via the CeMiSt systems. LCMS-based metabolomics provides an unparalleled service for the analysis of complex organic extracts. I am involved in implementing and developing tools on the GNPS platform, providing innovative metabolomics tools that aid in everything from drug discovery to chemical ecology.